宋艳秋

发布者:杜庆栋 发布时间:2023-12-20 浏览次数:845

    名:宋艳秋                      历:博士研究生

   称:讲师 

联系方式:E-mail: songyanqiu@lyu.edu.cn;电话:17627765906

个人简介

宋艳秋,女,博士,讲师,硕士生导师,中共党员,山东济宁人。2016年毕业于山东农业大学食品科学学院食品质量与安全专业,获工学学士学位;2019年毕业于山东农业大学和军事科学院军事医学研究院联合培养食品科学专业,获工学硕士学位;2023年毕业于南开大学化学学院高分子化学与物理专业,获理学博士学位。2023-至今,就职于临沂大学生命科学学院。主持和参加国家重点研发项目、国家自然科学基金面上项目和山东省自然科学基金青年项目等多项科研项目,在Journal of the American Chemical Society等学术期刊发表论文14余篇。

教学工作

承担本科生《有机化学》、《无机与分析化学》以及研究生《有机化学》课程

研究方向

形貌可控多肽自组装体的生物医学功能应用研究,主要通过对不同氨基酸残基的修饰改造,实现精确调控多肽纳米结构,结合功能肽或传统药物,制备多种形貌可控的多肽组装体系,构建具有不同治疗功能的多肽纳米诊疗平台

科研项目

1. 山东省自然科学基金青年项目,ZR2024QB100,肿瘤微环境自适应原位产热多肽纳米光热剂联合免疫激动剂用于肿瘤治疗的研究,2025.01-2027.1212万,主持

2. 国家自然科学基金面上项目,52073148,基于可适应性多肽纳米药物的肿瘤转移系统性治疗方法开发, 2021-01-012024-12-3159万元,参与

发表论文(#共同第一作者)

1. Hao Wang#Yanqiu Song#, Weishu Wang, Ninglin Chen, Binbin Hu, Xin Liu, Zeyu Zhang, and Zhilin Yu. Organelle-Mediated Dissipative Self-Assembly of Peptides in Living Cells. J. Am. Chem. Soc. 2023, 146330-341.

2. Yanqiu Song, Mingming Li, Na Song, Xin Liu and Zhilin Yu. Self-Amplification Assembly of Peptides in Macrophages for Enhanced Inflammatory Treatment. J. Am. Chem. Soc.2022144, 6907-6917.

3. Yanqiu Song, Qi Su, Huijuan Song and Zhilin Yu. Precisely Shaped Self-Adjuvanting Peptide Vaccines with Enhanced Immune Responses for HPV-Associated Cancer Therapy. ACS. Appl. Mater. Interfaces.202113, 49737-49753.

4. Yanqiu Song, Jialei Bai, Rong Zhang and Yuan Peng. LSPR-enhanced photonic crystal allows ultrasensitive and label-free detection of hazardous chemicals. Sensor. Actuat. B: Chem. 2020310, 127671.

5. Yanqiu Song, Jialei Bai and Yuan Peng. Michael-Addition-Mediated Photonic Crystals Allow Pretreatment-Free and Label-Free Sensoring of Ciprofloxacin in Fish Farming Water. Anal. Chem. 201890, 1388-1394.

6. Yanqiu Song, Zeyu Zhang, Yawei Cao and Zhilin Yu. Stimulus-responsive amino acids behind in situ assembled bioactive peptide materials. ChemBioChem 2022, e202200497.

7. Na Song, Yanqiu Song, Binbin Hu, Xin Liu, Xiunan Yu, Hao Zhou, Jiafu Long, Zhilin Yu. Persistent Endoplasmic Reticulum Stress Stimulated by Peptide Assemblies for Sensitizing Cancer Chemotherapy. Adv. Healthcare Mater.202211, 2202039.

8. Mian Tang, Yanqiu Song, Yi-Lin Lu, Ying-Ming Zhang and Yu Liu. Cyclodextrin-Activated Porphyrin Photosensitization for Boosting Self-Cleavable Drug Release. J. Med. Chem. 202265, 6764-6774.

9. Mingming Li, Yanqiu Song, Na Song and Zhilin Yu. Supramolecular Antagonists Promote Mitochondrial Dysfunction. Nano Letters202121, 5730-5737.

10. Na Song, Zhifei Zhou, Yanqiu Song and Zhilin Yu. In situ oxidation-regulated self-assembly of peptides into transformable scaffolds for cascade therapy. Nano Today 202138, 101198.

11. Xin Liu, Mingming Li, Juanzu Liu, Yanqiu Song and Zhilin Yu. In Situ Self-Sorting Peptide Assemblies in Living Cells for Simultaneous Organelle-Targeting. J. Am. Chem. Soc. 2022144, 9312-9323.

获批专利

1. 余志林;宋艳秋;一种形貌可控自佐剂宫颈癌多肽疫苗的制备及性能表征方法,2023-01-10,中国,ZL202110141555.8.

2. 余志林;宋艳秋;一种与酶共生增强炎症治疗的多肽自组装药物递送载体的制备方法, 2022-03-04,中国,202111438093.2.