郝丽

姓名：郝丽

学历：博士研究生

职称：讲师

联系方式：

E-mail: haolililili@163.com

电话：19506139196

个人简介

郝丽，女，博士，讲师，中共党员，山东潍坊人。2024年毕业于中国海洋大学食品科学与工程学院食品科学与工程专业，获工学博士学位。2025-至今，就职于临沂大学生命科学学院。在Trends in Food Science & Technology、Journal of Agricultural and Food Chemistry、Food Chemistry、Food Research International、Food & Function、Food Bioscience等杂志发表SCI论文20余篇。 

教学工作

承担本科生《食品专业英语》、《功能性食品》等课程。 

研究方向

1. 营养功能组分的识别与挖掘；2. 食源性活性肽的靶向制备及精细结构解析；3. 营养功能组分在细胞与动物模型中的生物学功能与分子作用机制解析。

论文及专著、教材

[1]  Li Hao, Yan Fan, Qiaoji Tian, Chaozhong Fan, Yanying Zhang, Ping Dong, Yanchao Wang, Hu Hou*. Current progress in umami peptides from blue foods: Preparation, screening, evaluation, synergistic effects, and taste mechanism, Trends in Food Science & Technology, 2024, 149, 104564.

[2]  Li Hao, Yulian Ding, Yan Fan, Qiaoji Tian, Yang Liu, Yueting Guo, Jian Zhang, Hu Hou*. Identification of hyperuricemia alleviating peptides from yellow tuna Thunnus albacares, Journal of Agricultural and Food Chemistry, 2024, 72, 12083-12099.

[3]  Li Hao, Chengcheng Ma, Zhaoxia Li, Yanchao Wang, Xue Zhao, Mingxiao Yu, Hu Hou*. Effects of type II collagen hydrolysates on osteoarthritis through the NF-κB, Wnt/β-catenin and MAPK pathways. Food & Function, 2022, 13(3): 1192-1205.

[4] Li Hao, Yulian Ding, Yan Fan*, Chensi Xia, Yuqian Meng, Qiannan Jia, Jian Zhang, Changhu Xue, Hu Hou*. New insights into anti-hyperuricemic effects of novel peptides from Antarctic Krill (Euphausia superba) by Q-Exactive Orbitrap MS-based non-targeted metabolomics, Food Bioscience, 2024, 59, 104063.

[5] Li Hao, Xinchang Gao, Tingyi Zhou, Jinxuan Cao, Yangying Sun, Yali Dang*, Daodong Pan*. Angiotensin I converting enzyme (ACE) inhibitory and antioxidant activity of umami peptides after in vitro gastrointestinal digestion. Journal of Agricultural and Food Chemistry, 2020, 68, 8232-8241. (一区TOP, IF: 6.1)

[6] Yali Dang, Li Hao, Jinxuan Cao, Yangying Sun, Xiaoqun Zeng, Zhen Wu, Daodong Pan*. Molecular docking and simulation of the synergistic effect between umami peptides, monosodium glutamate and taste receptor T1R1/T1R3. Food Chemistry, 2019, 271: 697-706. (高被引)

[7] Yali Dang, Li Hao, Tingyi Zhou, Jinxuan Cao, Yangying Sun, Daodong Pan*. Establishment of new assessment method for the synergistic effect between umami peptides and monosodium glutamate using electronic tongue. Food Research International, 2019, 121: 20-27.

[8] Yali Dang, Li Hao, Xiao Li, Yangying Sun, Daodong Pan*, Zhen Wu*, Jiamin Shen. Inhibitory mechanism of Chinese herbal medicine extracts on Escherichia coli and its application to fermented-bag sausage. LWT, 2021, 140, 110825.

[9] Qiaoji Tian, Li Hao, Qianqian Zhang, Huilin Huang, Chaoxin Tu, Yan Fan, Hu Hou*. Deciphering the calcium-binding mechanism of a novel cod bone-derived peptide: A synergistic experimental and computational analysis. Food Research International, 2025, 116490.

[10] Qiaoji Tian, Li Hao, Xue Song, Yang Liu, Chaozhong Fan, Qianqian Zhao, Hongwei Zhang, Hu Hou*. Isolation and differential structure characteristics of calcium-binding peptides derived from Pacific cod bones by hydroxyapatite affinity. Food Chemistry, 2024, 139268.

[11] 郝丽,李锋,李振兴,等.虚拟教研室在食品科学与工程专业上的应用[J].粮食科技与经济,2025,50(01):72-77.

[12] 侯虎, 郝丽, 樊燕. 一种金枪鱼源降尿酸混合物、组合物、制备方法及应用, 中国, CN202311220674.8 [P]. 2023,09,21.

[13] 侯虎, 郝丽, 薛长湖, 樊燕, 孟玉倩, 刘扬. 一种具有降尿酸活性的南极磷虾肽及其应用, 中国, CN202311480398.9 [P]. 2023,11,07.

[14] 侯虎, 郝丽, 樊燕, 赵雪. 一种包埋金枪鱼降尿酸肽的纳米脂质体, 中国, CN202410554742.2.

[15] 侯虎, 郝丽, 樊燕, 李师琦, 田巧基. 一种具有降尿酸和抗痛风功效的南极磷虾源多肽及其应用, 中国, CN202410551628.4.

[16] 侯虎, 郝丽, 樊燕. 一种黄鳍金枪鱼源降尿酸和抗痛风功能的新型七肽HF7及其应用, 中国, CN202410918339.3.

[17] 党亚丽, 郝丽, 高新昌, 潘道东. 兼具ACE抑制和抗氧化活性的肽及其制备方法和应用, 中国, CN201911001450.1 [P]. 2020,02,11.

[18] 党亚丽, 高新昌, 周亭屹, 郝丽. 西兰花蛋白来源的ACE和DPP-IV抑制肽及其制备方法和应用, 中国, CN201910963139.9 [P]. 2020,02,14.

[19] 党亚丽, 潘道东, 高新昌, 周亭屹, 郝丽, 曹锦轩. 一种西兰花蛋白来源的ACE抑制肽、ACE抑制肽酶切代谢产物及其制备方法和应用, 中国, CN201811444501.3 [P]. 2021,10,19.